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Obstructive Sleep Apnea Syndrome

Obstructive Sleep Apnea Syndrome. Clinical Manifestations.

Obstructive sleep apnea syndrome (OSAS) is a condition characterized by frequent pauses in breathing during sleep, usually accompanied by loud snoring. These pauses cut off the body’s oxygen supply for several seconds. As a result, the brain awakens and resumes breathing. This can happen hundreds of times throughout the night, resulting in shallow and unsteady sleep.

Clinical manifestations of OSA

More than 60% of patients with sleep apnea syndrome experience the following symptoms:

Loud snoring

  • Pauses in breathing
  • during sleep
  • Restless, unrefreshing sleep
  • Excessive daytime sleepiness
  • Frequent urination at night
  • Irritability, memory loss

Some patients, with more severe forms of the disease, experience the following symptoms:

  • Night attacks of suffocation
  • Night sweats
  • Morning headaches
  • High blood pressure
  • Decreased potency

What are the main risk factors?

Patients with comorbidities are at higher risk of developing OSA. Therefore, a diagnostic sleep study—polysomnography—is necessary in the presence of:

  1. Obesity (BMI >30)
  2. Heart failure
  3. Respiratory failure
  4. Metabolic syndrome
  5. Refractory hypertension (not controlled with a three-component treatment regimen)
  6. Coronary heart disease (class II-IV), atrial fibrillation, nocturnal arrhythmias, myocardial infarction, or a history of coronary heart disease surgery
  7. History of acute cerebrovascular accident (stroke).

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